Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 24;11(4):e006195. doi: 10.1136/jitc-2022-006195

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

(A) Example tumor-core mIF image of a patient with ISUP grade 4 ccRCC, using the lymphoid panel. Magnified area indicated by the gray box. (B) Differential cell densities stratified by histological zone. (C) Differential univariate cellular clustering, nK(75), in the tumor-core histological zone. (D) Differential bivariate clustering of tumor and immune cells, nK(75), in the tumor–stoma interface histological zone. ccRCC, clear cell renal cell carcinoma; mIF, multiplex immunofluorescence. ISUP = International Society of Urologic Pathology. Asterisk denotes p<0.05.