Table 2.
Patients with surgical treatment for cholangiocarcinoma recurrence.
| Location of recurrence | Age | ASA | Primary tumor TNMR |
Time to recurrence (months) | Surgery | R status | Surgical complications | Patient survival (months)* |
|
|---|---|---|---|---|---|---|---|---|---|
| 1 | Locoregional | 70 | II | HiCC T4N0M0 R0 |
22 | Tumor and RPV en-block resection. RPV reconstruction Hepaticojejnostomy reconstruction |
R0 | Bile Leakage | 9 |
| 2 | Locoregional | 57 | II | ICC T2N0M0 R0 |
65 | Exploratory laparotomy (Extended retroperitoneal infiltration) |
R2 | Acute respiratory failure | 21 |
| 3 | Locoregional | 72 | III | HiCC T2N+M0 R0 |
55 | Retrocaval LN and LRV en-block resection | R1 | 24 | |
| 4 | Locoregional | 73 | III | HiCC T2N+M0R1 |
7 | En-block tumor and PV resection and reconstruction. Hepaticojejunostomy reconstruction | R0 | Acute renal failure | 1 |
| 5 | Locoregional | 52 | III | ICC T4N0M0R2 |
22 | Exploratory laparotomy (Celiac trunk infiltration) |
R2 | 42 | |
| 6 | Locoregional | 48 | III | ICC T2N0M0R0 |
4 | Extrahepatic bile duct Hiliar LN. Bile duct resection. Hepaticojejunostomy |
R0 | 24 | |
| 7 | Locoregional | 73 | III | HiCC T1N0M0R0 |
3 | Exploratory laparotomy (Peritoneal carcinomatosis) |
R2 | SSI | 2 |
| 8 | Locoregional | 73 | II | HiCC T2N0M0R0 |
8 | Exploratory laparotomy (Peritoneal carcinomatosis) |
R2 | 3 | |
| 9 | Locoregional | 70 | II | HiCC T2N+M0R1 |
10 | Exploratory laparotomy (Peritoneal carcinomatosis) |
R2 | 2 | |
| 10 | Hepatic | 73 | III | ICC T1N0M0 R1 |
82 | S-V hepatectomy | R0 | Bronchoaspiration; Sepsis; MOD | 0 |
| 11 | Hepatic | 68 | III | ICC T2N0M0R0 |
6 | S-II, III and IVB tumorectomies | R1 | 39 | |
| 12 | Hepatic | 55 | II | DCC T2N+M0R0 |
15 | S-IVA hepatectomy Partial gastrectomy (Stomach infiltration) |
R0 | 20 | |
| 13 | Hepatic | 60 | III | HiCC T2N0M0R0 |
13 | S-I hepatectomy RFA S-IVA lesion |
R0 | Intraabdominal collection➔ Percutaneous drainage |
50 |
| 14 | Distant | 55 | II | HiCC T2N0M0 R0 |
22 | Exploratory laparotomy (Extended retroperitoneal infiltration) |
R2 | 31 | |
| 15 | Distant | 64 | III | HiCC T3N+M0R0 |
17 | S-III hepatectomy Hiliar LN |
R2 | SSI | 19 |
| 16 | Distant | 63 | III | HiCC T3N+M0R1 |
21 | Peritoneal implant resection (Peritoneal implants) | R0 | 15 | |
| 17 | Multiple (Locoregional + Hepatic) | 56 | II | ICC T2N0M0 R0 |
21 | S-V hepatectomy HA resection and reconstruction Hepatic hilium, celiac trunk, interaortocaval LN |
R1 | Intraabdominal collection➔ Percutaneous drainage |
7 |
| 18 | Multiple (locoregional +hepatic +distant) | 56 | III | HiCC T2N0M0R0 |
29 | Right anterior liver sectionectomy Hepaticojejunostomy reconstruction Partial gastrectomy |
R0 | Hemoperitoneum➔ HA bleeding | 1 |
DCC, distal cholangiocarcinoma; HA, hepatic artery; HiCC, hiliar cholangiocarcinoma; IA, intrabdominal; ICC, intrahepatic cholangiocarcinoma; LN, lymphadenectomy; LRV, left renal vein; MOD, multiorgan dysfunction; OS, overall survival; PV, portal vein; RFA, Radiofrequency ablation; RPV, right portal vein; SSI, surgical site infection; TNMR, TNMR stage of TMN classification.
* All patients were dead at the end of the follow-up.