TABLE 3.
Azurocidin and proteinase 3 do not inhibit the growth of H. capsulatum yeastsa
| Reagent | Concn (μg/ml) | % Inhibition of growthb |
|---|---|---|
| Azurocidin | 1 | −38 ± 34 |
| 5 | −14 ± 30 | |
| 10 | −23 ± 35 | |
| Proteinase 3 | 0.1 | −47 ± 32 |
| 0.5 | −40 ± 30 | |
| 1.0 | −33 ± 36 |
H. capsulatum yeasts (5 × 103) were incubated with various concentrations of azurocidin and proteinase 3 for 24 h at 37°C. The yeasts then were pulsed with [3H]leucine for an additional 24 h to quantitate the growth of the remaining yeasts.
Mean ± SEM (n = 7). The minus sign indicates that there was increased growth compared to yeasts cultured in control medium.