Figure 2.

Schematic representation of the available evidence on obstetric, neonatal, and long-term outcomes after embryo biopsy. Findings following biopsy of the polar body, blastomere, and trophectoderm (left to right, top row) are presented. The amber symbol represents weak and/or a controversial body of evidence, for which further research is required. The red symbol warns that no evidence on safety exists. The illustration was created with BioRender.com. BW, birthweight; GDM, gestational diabetes mellitus; HDP, hypertensive disorders of pregnancy; LBW, low birthweight; NICU, neonatal intensive care unit; PTD, preterm delivery; VLBW, very low birthweight.