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Reproductive performance of backcrossing Ryr2N1552S/+ with Ryr2R137W/+ parents and Plxnb2D1577E/+ with Plxnb2R465Q/+ parents. The number of pups per litter derived from pairs of Ryr2N1552S/+ with Ryr2R137W/+, Plxnb2D1577E/+ with Plxnb2R465Q/+ and WT with WT at the age of 8 weeks for 3 months. The results are shown as the mean ± SD, both female and male mice n = 8/group. *P < 0.05.
