Table I.
Clinical characteristics of unexplained recurrent miscarriage couples with verified candidate genes.
| Family ID | Family 1 | Family 2 | Family 3 | Family 4 |
|---|---|---|---|---|
| Female age (years) | 27 | 32 | 28 | 26 |
| Gravidity | 5 | 6 | 4 | 4 |
| Parity | 0 | 0 | 0 | 1 |
| History of previous miscarriages | 5 | 6 | 4 | 3 |
| Gestational age (wk+days) | 9+3 | 8+3 | 9+1 | 12 |
| Female BMI | 29.69 | 29.30 | 25.12 | 21.09 |
| Cycle length | 40∼50d | 28∼30d | 30∼50d | 28∼30d |
| Female karyotype | 46, XX | 46, XX | 46, XX | 46, XX |
| Morphology of uterus | Normal | Normal | Normal | Normal |
| Endometrial thickness (cm) | 0.85 | 0.75 | 0.75 | 0.8 |
| Autoimmune disease | （–） | （–） | （–） | （–） |
| Infection | （–） | （–） | （–） | （–） |
| Male age (years) | 35 | 34 | 30 | 35 |
| Male diagnosis | Teratozoospermia | Asthenozoospermia | Oligozoospermia | Teratozoospermia |
| Male karyotype | 46, XY | 46, XY | 46, XY | 46, XY |
| Villi karyotype | Euploid | Euploid | Euploid | Euploid |