Table 4.

Importance based on percentage of items used in the classification of profiles along dimensions of severity, risk of progression, and progression

	Severity		Risk of Progression		Progression
Domain with items used in classification	Rank between domains	Importance based on percentage selected	Rank between domains	Importance based on percentage selected	Rank between domains	Importance based on percentage selected
Demographics	5	Least influential	4	Less influential	—	Not ranked
Age, %		0		1
Sex, %		0		1
Race, %		0		1
Disease factors	4	Less influential	1	Most influential	—	Not ranked
Systemic sclerosis subtype, %		3		7
Disease duration, %		2		31
ANA status, %		0		1
Systemic sclerosis autoantibody status, %		2		11
Modified Rodnan Skin Score, %		0		1
Patient reported outcome measures	3	Influential	5	Least influential	3	Least influential
Baseline Dyspnoea Index/Transition Index, %		19		1		6
Leicester Cough Questionnaire, %		1		0		0
Patient global assessment, %		1		0		1
St George’s Respiratory Questionnaire, %		3		1		2
Spirometry and gas exchange	1	Most influential	2	Very influential	1	Most influential
Forced vital capacity, %		29		17		48
Diffusion capacity of carbon monoxide, %		11		5		6
Quantitative high resolution chest CT	2	Very influential	3	Influential	2	Influential
Total lung involvement, %		25		15		29
Total lung fibrosis, %		5		6		8