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. 2023 Mar 8;102(5):565–573. doi: 10.1177/00220345221149675

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© International Association for Dental Research and American Association for Dental, Oral, and Craniofacial Research 2023

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Snapshot of the differentially expressed genes between health (blue) and periodontal disease (red) in the mouse host oral metatranscriptome. (A) Breakdown of differentially expressed genes based on the presence and/or absence in health and disease with fold change >2. (B) Canonical coordinate analysis (CCA) plots showing the distribution of the 24 mouse samples based on host gene expression. (C) Percentage breakdown of the differentially expressed genes in health and disease based on protein class. (D) Percentage breakdown of the differentially expressed genes in health and disease based on biological process gene ontologies. (E) Percentage breakdown of the differentially expressed genes in health and disease based on molecular function gene ontologies.