Table 1.
Summary of proteins that are found in both EVs (http://www.microvesicles.org/) and mitochondria (https://www.proteinatlas.org/)
| No. | Gene symbol | Uniprot ID | Protein name(s) |
|---|---|---|---|
| 1 | DECR1 | Q16698 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1) |
| 2 | MRPS14 | O60783 | 28S ribosomal protein S14, mitochondrial (MRP-S14) (S14mt) (Mitochondrial small ribosomal subunit protein uS14m) |
| 3 | MRPS18B | Q9Y676 | 28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) (Mitochondrial small ribosomal subunit protein bS18b) (Mitochondrial small ribosomal subunit protein mS40) |
| 4 | MRPS23 | Q9Y3D9 | 28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt) (Mitochondrial small ribosomal subunit protein mS23) |
| 5 | MRPS26 | Q9BYN8 | 28S ribosomal protein S26, mitochondrial (MRP-S26) (S26mt) (28S ribosomal protein S13, mitochondrial) (MRP-S13) (S13mt) (Mitochondrial small ribosomal subunit protein mS26) |
| 6 | MRPS27 | Q92552 | 28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27) (Mitochondrial small ribosomal subunit protein mS27) |
| 7 | DAP3 | P51398 | 28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein) (Mitochondrial small ribosomal subunit protein mS29) |
| 8 | MRPS31 | Q92665 | 28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt) (Imogen 38) (Mitochondrial small ribosomal subunit protein mS31) |
| 9 | MRPS35 | P82673 | 28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt) (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt) (Mitochondrial small ribosomal subunit protein mS35) |
| 10 | BCKDHB | P21953 | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta) |
| 11 | MRPL2 | Q5T653 | 39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2) (Mitochondrial large ribosomal subunit protein uL2m) |
| 12 | MRPL21 | Q7Z2W9 | 39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21) (Mitochondrial large ribosomal subunit protein bL21m) |
| 13 | MRPL23 | Q16540 | 39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23) (L23 mitochondrial-related protein) (Mitochondrial large ribosomal subunit protein uL23m) (Ribosomal protein L23-like) |
| 14 | MRPL36 | Q9P0J6 | 39S ribosomal protein L36, mitochondrial (L36mt) (MRP-L36) (BRCA1-interacting protein 1) (Mitochondrial large ribosomal subunit protein bL36m) |
| 15 | MRPL40 | Q9NQ50 | 39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40) (Mitochondrial large ribosomal subunit protein mL40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome) (Up-regulated in metastasis) |
| 16 | MRPL43 | Q8N983 | 39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Mitochondrial large ribosomal subunit protein mL43) (Mitochondrial ribosomal protein bMRP36a) |
| 17 | MRPL44 | Q9H9J2 | 39S ribosomal protein L44, mitochondrial (L44mt) (MRP-L44) (EC 3.1.26.-) (Mitochondrial large ribosomal subunit protein mL44) |
| 18 | MRPL46 | Q9H2W6 | 39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (Mitochondrial large ribosomal subunit protein mL46) (P2ECSL) |
| 19 | MRPL52 | Q86TS9 | 39S ribosomal protein L52, mitochondrial (L52mt) (MRP-L52) (Mitochondrial large ribosomal subunit protein mL52) |
| 20 | MPST | P25325 | 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) |
| 21 | HPDL | Q96IR7 | 4-hydroxyphenylpyruvate dioxygenase-like protein (HPD-like protein) (EC 1.13.-.-) (Glyoxalase domain-containing protein 1) |
| 22 | NT5DC3 | Q86UY8 | 5′-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase) |
| 23 | RPL7L1 | Q6DKI1 | 60S ribosomal protein L7-like 1 (Large ribosomal subunit protein uL30-like 1) |
| 24 | ADAMTS16 | Q8TE57 | A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-) |
| 25 | SMPDL3A | Q92484 | Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-) |
| 26 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) |
| 27 | AGK | Q53H12 | Acylglycerol kinase, mitochondrial (hAGK) (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (HsMuLK) (MuLK) (Multi-substrate lipid kinase) |
| 28 | FAHD1 | Q6P587 | Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (FAH domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) (YisK-like protein) |
| 29 | NUDT9 | Q9BW91 | ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9) |
| 30 | AARS2 | Q5JTZ9 | Alanine–tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) |
| 31 | AARS2 | Q5JTZ9 | Alanine–tRNA ligase, mitochondrial |
| 32 | ALDH1B1 | P30837 | Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) |
| 33 | ALDH7A1 | P49419 | Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) |
| 34 | AASS | Q9UDR5 | Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] |
| 35 | MAOA | P21397 | Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) |
| 36 | ADGB | Q8N7X0 | Androglobin (Calpain-7-like protein) |
| 37 | ANKRD34B | A5PLL1 | Ankyrin repeat domain-containing protein 34B |
| 38 | ARMCX1 | Q9P291 | Armadillo repeat-containing X-linked protein 1 (ARM protein lost in epithelial cancers on chromosome X 1) (Protein ALEX1) |
| 39 | ARMCX2 | Q7L311 | Armadillo repeat-containing X-linked protein 2 (ARM protein lost in epithelial cancers on chromosome X 2) (Protein ALEX2) |
| 40 | DARS2 | Q6PI48 | Aspartate–tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) |
| 41 | ATP5MF | P56134 | ATP synthase subunit f, mitochondrial (ATP synthase membrane subunit f) |
| 42 | PFKL | P17858 | ATP-dependent 6-phosphofructokinase, liver type (ATP-PFK) (PFK-L) (EC 2.7.1.11) (6-phosphofructokinase type B) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphohexokinase) |
| 43 | CLPX | O76031 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
| 44 | DHX30 | Q7L2E3 | ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) |
| 45 | YME1L1 | Q96TA2 | ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1) |
| 46 | ATRNL1 | Q5VV63 | Attractin-like protein 1 |
| 47 | AURKAIP1 | Q9NWT8 | Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38) |
| 48 | CD72 | P21854 | B-cell differentiation antigen CD72 (Lyb-2) (CD antigen CD72) |
| 49 | BOLA3 | Q53S33 | BolA-like protein 3 |
| 50 | BDNF | P23560 | Brain-derived neurotrophic factor (BDNF) (Abrineurin) [Cleaved into: BDNF precursor form (ProBDNF)] |
| 51 | BRI3BP | Q8WY22 | BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto-oncogene-binding protein KG19) (HCCRBP-1) |
| 52 | KCTD6 | Q8NC69 | BTB/POZ domain-containing protein KCTD6 (KCASH3 protein) (Potassium channel tetramerization domain-containing protein 6) |
| 53 | CALHM2 | Q9HA72 | Calcium homeostasis modulator protein 2 (Protein FAM26B) |
| 54 | CASQ1 | P31415 | Calsequestrin-1 (Calmitine) (Calsequestrin, skeletal muscle isoform) |
| 55 | CPT2 | P23786 | Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) |
| 56 | CASP3 | P42574 | Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] |
| 57 | SLC44A1 | Q8WWI5 | Choline transporter-like protein 1 (CDw92) (Solute carrier family 44 member 1) (CD antigen CD92) |
| 58 | CBX6 | O95503 | Chromobox protein homolog 6 |
| 59 | C21orf2 | O43822 | Cilia- and flagella-associated protein 410 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2) |
| 60 | CNKSR3 | Q6P9H4 | Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein) |
| 61 | ATG4D | Q86TL0 | Cysteine protease ATG4D (EC 3.4.22.-) (AUT-like 4 cysteine endopeptidase) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (Autophagy-related protein 4 homolog D) [Cleaved into: Cysteine protease ATG4D, mitochondrial] |
| 62 | COX7A2L | O14548 | Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7a-related protein) (Cytochrome c oxidase subunit VIIa-related protein) (EB1) |
| 63 | CYC1 | P08574 | Cytochrome c1, heme protein, mitochondrial (EC 7.1.1.8) (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1) |
| 64 | DYNC2H1 | Q8NCM8 | Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) |
| 65 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 |
| 66 | DHRS2 | Q13268 | Dehydrogenase/reductase SDR family member 2, mitochondrial (EC 1.1.1.-) (Dicarbonyl reductase HEP27) (Protein D) (Short chain dehydrogenase/reductase family 25C member 1) |
| 67 | DHRS7 | Q9Y394 | Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) |
| 68 | DEPTOR | Q8TB45 | DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6) |
| 69 | DIABLO | Q9NR28 | Diablo homolog, mitochondrial |
| 70 | DIABLO | Q9NR28 | Diablo homolog, mitochondrial (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) |
| 71 | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) |
| 72 | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) |
| 73 | DHODH | Q02127 | Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) |
| 74 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog) |
| 75 | DNLZ | Q5SXM8 | DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein) |
| 76 | DMRTA2 | Q96SC8 | Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) |
| 77 | OPA1 | O60313 | Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1) [Cleaved into: Dynamin-like 120 kDa protein, form S1] |
| 78 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rabring 7) (Zinc finger protein 364) |
| 79 | SIAH1 | Q8IUQ4 | E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a) |
| 80 | EML6 | Q6ZMW3 | Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) |
| 81 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1) |
| 82 | TSFM | P43897 | Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) |
| 83 | ECI2 | O75521 | Enoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1) |
| 84 | EIF4E2 | O60573 | Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3) |
| 85 | SLC1A3 | P43003 | Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3) |
| 86 | EXOC3 | O60645 | Exocyst complex component 3 (Exocyst complex component Sec6) |
| 87 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) |
| 88 | FASTK | Q14296 | Fas-activated serine/threonine kinase (FAST kinase) (EC 2.7.11.8) |
| 89 | FSTL4 | Q6MZW2 | Follistatin-related protein 4 (Follistatin-like protein 4) |
| 90 | FOXN4 | Q96NZ1 | Forkhead box protein N4 |
| 91 | FXN | Q16595 | Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56–210) (m56-FXN); Frataxin(78–210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81–210)) (m81-FXN)] |
| 92 | LGALS2 | P05162 | Galectin-2 (Gal-2) (Beta-galactoside-binding lectin L-14-II) (HL14) (Lactose-binding lectin 2) (S-Lac lectin 2) |
| 93 | GDAP1 | Q8TB36 | Ganglioside-induced differentiation-associated protein 1 (GDAP1) |
| 94 | GSE1 | Q14687 | Genetic suppressor element 1 |
| 95 | FP565260.6 | A0A0B4J2D5 | Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial (Keio novel protein-I) (KNP-I) (Protein GT335) (Protein HES1) |
| 96 | GLDC | P23378 | Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)) |
| 97 | GADD45GIP1 | Q8TAE8 | Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Mitochondrial large ribosomal subunit protein mL64) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein) |
| 98 | AC093155.3 | Q7LGA3 | Heparan sulfate 2-O-sulfotransferase 1 |
| 99 | HS2ST1 | Q7LGA3 | Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-) |
| 100 | HHIPL2 | Q6UWX4 | HHIP-like protein 2 |
| 101 | HIGD1A | Q9Y241 | HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a) |
| 102 | HIGD2A | Q9BW72 | HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b) |
| 103 | HINT3 | Q9NQE9 | Histidine triad nucleotide-binding protein 3 (HINT-3) (EC 3.-.-.-) |
| 104 | NSD3 | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1) |
| 105 | HCFC1 | P51610 | Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] |
| 106 | HSDL1 | Q3SXM5 | Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3) |
| 107 | PLD5 | Q8N7P1 | Inactive phospholipase D5 (Inactive PLD 5) (Inactive choline phosphatase 5) (Inactive phosphatidylcholine-hydrolyzing phospholipase D5) (PLDc) |
| 108 | ITGB5 | P18084 | Integrin beta-5 |
| 109 | ICAM3 | P32942 | Intercellular adhesion molecule 3 (ICAM-3) (CDw50) (ICAM-R) (CD antigen CD50) |
| 110 | ILF3 | Q12906 | Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80) |
| 111 | IFT27 | Q9BW83 | Intraflagellar transport protein 27 homolog (Putative GTP-binding protein RAY-like) (Rab-like protein 4) |
| 112 | ISOC2 | Q96AB3 | Isochorismatase domain-containing protein 2 |
| 113 | IDH3G | P51553 | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD( +)-specific ICDH subunit gamma) |
| 114 | IVD | P26440 | Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1) |
| 115 | KLHL29 | Q96CT2 | Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9) |
| 116 | KLC4 | Q9NSK0 | Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8) |
| 117 | LRRD1 | A4D1F6 | Leucine-rich repeat and death domain-containing protein 1 |
| 118 | LIAS | O43766 | Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase) |
| 119 | LONP1 | P36776 | Lon protease homolog, mitochondrial (EC 3.4.21.53) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15) |
| 120 | ACSL5 | Q9ULC5 | Long-chain-fatty-acid–CoA ligase 5 (EC 6.2.1.3) (Arachidonate–CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 5) (LACS 5) |
| 121 | LRP12 | Q9Y561 | Low-density lipoprotein receptor-related protein 12 (LDLR-related protein 12) (LRP-12) (Suppressor of tumorigenicity 7 protein) |
| 122 | LRP4 | O75096 | Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) |
| 123 | MFSD12 | Q6NUT3 | Major facilitator superfamily domain-containing protein 12 |
| 124 | XK | P51811 | Membrane transport protein XK (Kell complex 37 kDa component) (Kx antigen) (XK-related protein 1) |
| 125 | MBLAC2 | Q68D91 | Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-) |
| 126 | MTX2 | O75431 | Metaxin-2 (Mitochondrial outer membrane import complex protein 2) |
| 127 | C19orf70 | Q5XKP0 | MICOS complex subunit MIC13 (Protein P117) |
| 128 | APOO | Q9BUR5 | MICOS complex subunit MIC26 (Apolipoprotein O) (MICOS complex subunit MIC23) (Protein FAM121B) |
| 129 | MGST1 | P10620 | Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I) |
| 130 | SLC25A10 | Q9UBX3 | Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10) |
| 131 | SLC25A22 | Q9H936 | Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H( +) symporter 1) (Solute carrier family 25 member 22) |
| 132 | SLC25A18 | Q9H1K4 | Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H( +) symporter 2) (Solute carrier family 25 member 18) |
| 133 | TIMM13 | Q9Y5L4 | Mitochondrial import inner membrane translocase subunit Tim13 |
| 134 | PAM16 | Q9Y3D7 | Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16) |
| 135 | TIMM50 | Q3ZCQ8 | Mitochondrial import inner membrane translocase subunit TIM50 |
| 136 | TOMM40 | O96008 | Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5) |
| 137 | CCDC51 | Q96ER9 | Mitochondrial potassium channel (MITOK) (Coiled-coil domain-containing protein 51) |
| 138 | ABCB8 | Q9NUT2 | Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial ATP-binding cassette 1) (M-ABC1) (Mitochondrial sulfonylurea-receptor) (MITOSUR) |
| 139 | KIAA0391 | O15091 | Mitochondrial ribonuclease P catalytic subunit (EC 3.1.26.5) (Mitochondrial ribonuclease P protein 3) (Mitochondrial RNase P protein 3) (Protein only RNase P catalytic subunit) |
| 140 | SLC25A37 | Q9NYZ2 | Mitoferrin-1 (Mitochondrial iron transporter 1) (Mitochondrial solute carrier protein) (Solute carrier family 25 member 37) |
| 141 | MOCOS | Q96EN8 | Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (hMCS) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) |
| 142 | MORN1 | Q5T089 | MORN repeat-containing protein 1 |
| 143 | MYL3 | P08590 | Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb) |
| 144 | B3GNT4 | Q9C0J1 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (EC 2.4.1.149) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4) (BGnT-4) (Beta-1,3-Gn-T4) (Beta-1,3-N-acetylglucosaminyltransferase 4) (Beta3Gn-T4) |
| 145 | NNT | Q13423 | NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) |
| 146 | NDUFA12 | Q9UI09 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (13 kDa differentiation-associated protein) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2) |
| 147 | NDUFA9 | Q16795 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) |
| 148 | NDUFB1 | O75438 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (Complex I-MNLL) (CI-MNLL) (NADH-ubiquinone oxidoreductase MNLL subunit) |
| 149 | NDUFB4 | O95168 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit) |
| 150 | NDUFB5 | O43674 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit) |
| 151 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit) |
| 152 | NDUFV2 | P19404 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit) |
| 153 | NDUFS3 | O75489 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit) |
| 154 | CYB5R1 | Q9UHQ9 | NADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (Humb5R2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2) |
| 155 | SLC11A1 | P49279 | Natural resistance-associated macrophage protein 1 (NRAMP 1) (Solute carrier family 11 member 1) |
| 156 | NGRN | Q9NPE2 | Neugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G) |
| 157 | NGDN | Q8NEJ9 | Neuroguidin (Centromere accumulated nuclear protein 1) (CANu1) (EIF4E-binding protein) |
| 158 | SLC3A1 | Q07837 | Neutral and basic amino acid transport protein rBAT (NBAT) (D2h) (Solute carrier family 3 member 1) (b(0, +)-type amino acid transport protein) |
| 159 | NLRX1 | Q86UT6 | NLR family member X1 (Caterpiller protein 11.3) (CLR11.3) (Nucleotide-binding oligomerization domain protein 26) (Nucleotide-binding oligomerization domain protein 5) (Nucleotide-binding oligomerization domain protein 9) |
| 160 | NACC2 | Q96BF6 | Nucleus accumbens-associated protein 2 (NAC-2) (BTB/POZ domain-containing protein 14A) (Repressor with BTB domain and BEN domain) |
| 161 | REXO2 | Q9Y3B8 | Oligoribonuclease, mitochondrial (EC 3.1.-.-) (RNA exonuclease 2 homolog) (Small fragment nuclease) |
| 162 | OAT | P04181 | Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine delta-aminotransferase) (Ornithine–oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form] |
| 163 | PAX9 | P55771 | Paired box protein Pax-9 |
| 164 | Q9HBH1 | Peptide deformylase, mitochondrial (EC 3.5.1.88) (Polypeptide deformylase) | |
| 165 | FKBP8 | Q14318 | Peptidyl-prolyl cis–trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase) |
| 166 | MRPL58 | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Digestion substraction 1) (DS-1) (Immature colon carcinoma transcript 1 protein) (Mitochondrial large ribosomal subunit protein mL62) |
| 167 | GPX4 | P36969 | Phospholipid hydroperoxide glutathione peroxidase (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4) |
| 168 | PIWIL4 | Q7Z3Z4 | Piwi-like protein 4 |
| 169 | PCBP3 | P57721 | Poly(rC)-binding protein 3 (Alpha-CP3) (PCBP3-overlapping transcript) (PCBP3-overlapping transcript 1) |
| 170 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein) |
| 171 | KCNH3 | Q9ULD8 | Potassium voltage-gated channel subfamily H member 3 (Brain-specific eag-like channel 1) (BEC1) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Voltage-gated potassium channel subunit Kv12.2) |
| 172 | PCYOX1L | Q8NBM8 | Prenylcysteine oxidase-like (EC 1.8.3.-) |
| 173 | DPY19L2 | Q6NUT2 | Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2) |
| 174 | CARS2 | Q9HA77 | Probable cysteine–tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) |
| 175 | EARS2 | Q5JPH6 | Probable glutamate–tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) |
| 176 | LARS2 | Q15031 | Probable leucine–tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) |
| 177 | PSTPIP2 | Q9H939 | Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2) |
| 178 | PSMG4 | Q5JS54 | Proteasome assembly chaperone 4 (PAC-4) (hPAC4) |
| 179 | SELENOO | Q9BVL4 | Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.n1) (Selenoprotein O) (SelO) |
| 180 | ATOH1 | Q92858 | Protein atonal homolog 1 (Class A basic helix-loop-helix protein 14) (bHLHa14) (Helix-loop-helix protein hATH-1) (hATH1) |
| 181 | FAM171B | Q6P995 | Protein FAM171B |
| 182 | FAM181B | A6NEQ2 | Protein FAM181B |
| 183 | FAM234A | Q9H0X4 | Protein FAM234A (Protein ITFG3) |
| 184 | FAM83F | Q8NEG4 | Protein FAM83F |
| 185 | JARID2 | Q92833 | Protein Jumonji (Jumonji/ARID domain-containing protein 2) |
| 186 | CCDC58 | Q4VC31 | Protein MIX23 (Coiled-coil domain-containing protein 58) |
| 187 | SCO2 | O43819 | Protein SCO2 homolog, mitochondrial |
| 188 | SCO2 | O43819 | Protein SCO2 homolog, mitochondrial |
| 189 | PCMTD2 | Q9NV79 | Protein-l-isoaspartate O-methyltransferase domain-containing protein 2 |
| 190 | PPOX | P50336 | Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) |
| 191 | PDK3 | Q15120 | Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3 |
| 192 | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1) |
| 193 | RAB38 | P57729 | Ras-related protein Rab-38 (Melanoma antigen NY-MEL-1) |
| 194 | RIMS3 | Q9UJD0 | Regulating synaptic membrane exocytosis protein 3 (Nim3) (RIM3 gamma) (Rab-3-interacting molecule 3) (RIM 3) |
| 195 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 (RMD-3) (hRMD-3) (Cerebral protein 10) (Protein FAM82A2) (Protein FAM82C) (Protein tyrosine phosphatase-interacting protein 51) (TCPTP-interacting protein 51) |
| 196 | RTKN | Q9BST9 | Rhotekin |
| 197 | RPS6KA6 | Q9UK32 | Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) |
| 198 | GFM2 | Q969S9 | Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2) (Elongation factor G2) (hEFG2) |
| 199 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) |
| 200 | ANKRD44 | Q8N8A2 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) |
| 201 | ANKRD52 | Q8NB46 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) (Ankyrin repeat domain-containing protein 52) |
| 202 | SARS2 | Q9NP81 | Serine–tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) |
| 203 | DHRS3 | O75911 | Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1) |
| 204 | ACADS | P16219 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase) |
| 205 | SLC6A13 | Q9NSD5 | Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) |
| 206 | SPATA2L | Q8IUW3 | Spermatogenesis-associated protein 2-like protein (SPATA2-like protein) |
| 207 | CYP27A1 | Q02318 | Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) |
| 208 | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) |
| 209 | SDHB | P21912 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) |
| 210 | SUCLG1 | P53597 | Succinate–CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) |
| 211 | SUCLG2 | Q96I99 | Succinate–CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) |
| 212 | SDC3 | O75056 | Syndecan-3 (SYND3) |
| 213 | TTC27 | Q6P3X3 | Tetratricopeptide repeat protein 27 (TPR repeat protein 27) |
| 214 | TTC28 | Q96AY4 | Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) |
| 215 | TTC9B | Q8N6N2 | Tetratricopeptide repeat protein 9B (TPR repeat protein 9B) |
| 216 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6) |
| 217 | TLR2 | O60603 | Toll-like receptor 2 (EC 3.2.2.6) (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282) |
| 218 | TRABD | Q9H4I3 | TraB domain-containing protein (Protein TTG2) |
| 219 | ENY2 | Q9NPA8 | Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog) |
| 220 | TFAP4 | Q01664 | Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41) |
| 221 | GUF1 | Q8N442 | Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase) |
| 222 | MTIF3 | Q9H2K0 | Translation initiation factor IF-3, mitochondrial (IF-3(Mt)) (IF-3Mt) (IF3(mt)) (IF3mt) |
| 223 | TMEM141 | Q96I45 | Transmembrane protein 141 |
| 224 | TMEM70 | Q9BUB7 | Transmembrane protein 70, mitochondrial |
| 225 | TMPPE | Q6ZT21 | Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) |
| 226 | TNRC18 | O15417 | Trinucleotide repeat-containing gene 18 protein (Long CAG trinucleotide repeat-containing gene 79 protein) |
| 227 | TRMT10C | Q7L0Y3 | tRNA methyltransferase 10 homolog C (HBV pre-S2 trans-regulated protein 2) (Mitochondrial ribonuclease P protein 1) (Mitochondrial RNase P protein 1) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-) (tRNA (adenine(9)-N(1))-methyltransferase) (EC 2.1.1.218) (tRNA (guanine(9)-N(1))-methyltransferase) (EC 2.1.1.221) |
| 228 | PUS1 | Q9Y606 | tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA pseudouridine(38–40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I) |
| 229 | TNFRSF19 | Q9NS68 | Tumor necrosis factor receptor superfamily member 19 (TRADE) (Toxicity and JNK inducer) |
| 230 | YARS2 | Q9Y2Z4 | Tyrosine–tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
| 231 | OTULIN | Q96BN8 | Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby) |
| 232 | UBE3C | Q15386 | Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (HectH2) |
| 233 | CMPK2 | Q5EBM0 | UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) |
| 234 | C7orf31 | Q8N865 | Uncharacterized protein C7orf31 |
| 235 | KIAA0930 | Q6ICG6 | Uncharacterized protein KIAA0930 |
| 236 | VASN | Q6EMK4 | Vasorin (Protein slit-like 2) |
| 237 | ACADVL | P49748 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9) |
| 238 | VWA5B1 | Q5TIE3 | von Willebrand factor A domain-containing protein 5B1 |
| 239 | XPNPEP3 | Q9NQH7 | Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) |
| 240 | ZCCHC24 | Q8N2G6 | Zinc finger CCHC domain-containing protein 24 |
| 241 | ZNF428 | Q96B54 | Zinc finger protein 428 (Enzyme-like protein PIT13) |
| 242 | ZNF625 | Q96I27 | Zinc finger protein 625 |
| 243 | ZNF782 | Q6ZMW2 | Zinc finger protein 782 |
| 244 | HKR1 | P10072 | Zinc finger protein 875 (Krueppel-related zinc finger protein 1) (Protein HKR1) |