Table 4.
Comparisons of clinical and biochemical features before and after 8 weeks intervention
| Variable | HEMO (Mean ± SD) | Placebo (Mean ± SD) | p Value∏ | |
|---|---|---|---|---|
| Weight (kg) | Before | 77.41 ± 14.98 | 77.42 ± 13.09 |
0.63 0.31 ‡‡ |
| After | 75.78 ± 15.29 | 77.80 ± 12.60 | ||
| mean change | -1.63 ± 6.75 | 0.38 ± 1.96 | ||
| p Value## | 0.19▲ | 0.18▲ | ||
| BMI (kg/m2) | Before | 28.61 ± 4.34 | 28.34 ± 3.96 |
0.52 0.11 |
| After | 28.03 ± 4.30 | 28.53 ± 3.80 | ||
| mean change | -0.58 ± 2.57 | 0.19 ± 0 .73 | ||
| p Value## | 0.97▲ | 0.21▲ | ||
| WC/Hip | Before | 0.93 ± 0.04 | 0.93 ± 0.05 |
0.63 0.62 ‡‡ |
| After | 0.93 ± 0.04 | 0.93 ± 0.05 | ||
| mean change | 0.001 ± 0.02 | 0.004 ± 0.03 | ||
| p Value## | 0.26▲ | 0.93▲ | ||
| FBS (mg/d) | Before | 146.26 ± 35.77 | 140.61 ± 37.69 |
0.75 0.75 ‡‡ |
| After | 149.82 ± 33.56 | 150.76 ± 35.34 | ||
| mean change | 3.57 ± 16.22 | 10.62 ± 18.79 | ||
| p Value## | 0.30▲ | 0.02▲ | ||
| Depression | Before | 18.00 ± 10.30 | 14.28 ± 5.11 |
0.52 0.001 ‡‡ |
| After | 14.08 ± 7.63 | 14.23 ± 5.43 | ||
| mean change | -3.91 ± 4.48 | -0.04 ± 2.67 | ||
| p Value## | 0.001▲ | 0.71▲ | ||
| Anxiety | Before | 11.82 ± 8.10 | 8.09 ± 5.32 |
0.79 0.04 ‡‡ |
| After | 9.78 ± 7.60 | 8.33 ± 5.69 | ||
| mean change | -2.04 ± 3.49 | 0.23 ± 3.75 | ||
| p Value## | 0.01▲ | 0.51▲ | ||
| Sleep Quality | Before | 4.69 ± 2.56 | 4.61 ± 3.89 |
0.97 0.15 ‡‡ |
| After | 4.00 ± 2.21 | 4.42 ± 3.32 | ||
| mean change | -0.69 ± 1.74 | -0.19 ± 1.20 | ||
| p Value## | 0.08▲ | 0.58▲ | ||
| Hs-CRP (mg/L) | Before | 1.95 ± 1.84 | 2.13 ± 2.82 |
0.63 0.11 ‡‡ |
| After | 1.60 ± 1.86 | 2.20 ± 2.51 | ||
| mean change | -0.34 ± 1.03 | 0.65 ± 0.75 | ||
| p Value## | 0.13▲ | 0.62▲ | ||
|
Systolic blood pressure (mm Hg) |
Before | 13.84 ± 2.05 | 12.92 ± 1.42 |
0.69 0.06 ‡‡ |
| After | 13.52 ± 1.95 | 13.50 ± 1.64 | ||
| mean change | -0.32 ± 1.49 | 0.57 ± 1.49 | ||
| p Value## | 0.28▲ | 0.11▲ | ||
|
Diastolic blood pressure (mm Hg) |
Before | 8.58 ± 1.19 | 8.11 ± 1.27 |
0.62 0.26 ‡‡ |
| After | 8.48 ± 1.22 | 8.33 ± 1.16 | ||
| mean change | -0.1 ± 0.83 | 0.21 ± 0.71 | ||
| p Value## | 0.93▲ | 0.20▲ | ||
Values are presented as mean ± standard deviation. p Value∏ (p < 0.05) for variable comparing between the two groups at the end of the intervention.p Value## for variable comparing within the two groups at the end of the intervention. Calculated by ▲Wilcoxon signed-ranks test. p Value‡‡ for mean changes comparing between the two groups at the end of the intervention
BMI body mass index, WC waist circumference, FBS fasting blood sugar, HEMO hydroalcoholic extract of M. officinalis; hs-CRP high-sensitivity C-reactive protein, DBP diastolic blood pressure, SBP systolic blood pressure