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. 2023 May 2;21:145. doi: 10.1186/s12951-023-01889-0

Fig. 1.

Fig. 1

Solid lipid nanoparticle (SLN) synthesis procedure and GI flora-triggered drug topical release system. (A) Synthetic route of NaCS-C12. (B) The procedure of LBL self-assembly on the SLN template forming polyelectrolyte complex (PEC) layers. (C) The release mechanism of BUD from different generations of SLNs in different GI tracts