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. 2023 May 2:1–35. Online ahead of print. doi: 10.1007/s43630-023-00370-z

Fig. 7.

Fig. 7

Conceptual model of inactivation mechanisms by solar radiation in viruses and bacteria. The direct mechanism involves photon absorption by viral or bacterial proteins or nucleic acids (orange stars), which triggers their photodegradation. In indirect mechanisms, the photon is absorbed by a sensitiser (Sens) present either inside (endogenous) or outside (exogenous) the pathogen. This process generates photochemically produced reactive intermediates (PPRIs) that include, among others, singlet oxygen, hydroxyl radicals, and triplet excited states that further damage the pathogen’s proteins and nucleic acids (orange stars). Green shapes represent proteins. Modified from [78]