Figure 1. Phylogenetic position of hagfish and multigene support for the cyclostome hypothesis.
a, Picture of a brown hagfish, Eptatretus atami (photo credit K. Kubokawa). b, Distinct hypothesis regarding early vertebrate evolution. c, Phylogenetic reconstruction of deuterostome relationships using 176 genes and 61,939 positions selected as least saturated using a site-heterogeneous model (CAT+GTR). topology is robust to composition heterogeneity and similar to what was obtained for all 1,467 genes using site-homogeneous models (Figure S3).