FIG. 2.

GBS III CPS-specific IgA and IgG titers in serum and mucosa after i.n. immunization with a CPS-rCTB conjugate at different dosages and schedules. The conjugate doses used were 10 μg of CPS plus 1.5 μg of CT (horizontal striped bars), 30 μg of CPS plus 1.5 μg of CT (white bars), and 80 μg of CPS plus 1.5 μg of CT (vertical striped bars), which were divided and given on three consecutive days per round. Black bars represent the group of mice immunized with 30 μg of CPS plus 2.5 μg of CT given on one occasion per round. Stars denote significant differences between two groups (∗∗, P < 0.01).