Table 1.

Summary table of uterine fibroid with cystic degeneration.

Etiology	A progressive increase in the size of the uterine fibroid causes its own blood supply to be outgrown, allowing only the periphery to be sufficiently supplied and leaving the core relatively avascular. Thus, leading to various types of degeneration, one of them being cystic.
Incidence	Cystic degeneration represents only 4% of all uterine fibroid cases.
Gender Ratio	It occurs exclusively in females
Age prediction	The incidence of uterine fibroids increases in women above 30 years of age. Cystic degeneration of uterine fibroids is more commonly found in post-menopausal women.
Risk factors	Uterine fibroid: Age (>30 years), obesity, family history of uterine fibroids, hypertension, no history of pregnancy, vitamin D deficiency, and African American ethnicity. Cystic degeneration: Age (post-menopausal) and interstitial type of fibroid.
Treatment	The most performed procedure is exploratory laparotomy for cystic degenerated uterine fibroid. Recent reports successfully conducted laparoscopic removal of the degenerating fibroid.
Prognosis	The prognosis of cystic degenerated uterine fibroids is similar to uterine fibroids without degeneration. Prognosis is excellent in most patients. Although rare, fibroids may cause serious complications in pregnancy, such as pain, preterm labor, uterine rupture, malpresentation, and postpartum hemorrhage.
Findings on imaging	Ultrasound: - The fibroid will appear as a hypoechoic or heterogeneous mass. - There will be minimal echogenicity and irregular anechoic areas in cystic degeneration, possibly with a high level of echo and distal acoustic shadowing. MRI: - T2W imaging: Uterine fibroid will show lower signal intensity areas than normal myometrium. - T1W imaging: fibroids will show isointense areas compared to normal myometrium. - On cystic degeneration, there will be less signal intensity on T1W and increased signal intensity on T2W imaging