TABLE 1.

Univariate Meta-Regression for Mortality Rate

Covariate	Coefficient	Lower Bound–Upper Bound	p
First-half 2020	0.182	–3.279 to 3.642	0.918
Second-half 2020	0.692	–0.805 to 2.190	0.365
First-half 2021	–0.726	–2.541 to 1.089	0.433
Second-half 2021	2.443	–1.290 to 6.176	0.200
Venoarterial ECMO	1.524	–3.573 to 6.622	0.558
Venovenous ECMO	–1.524	–6.622 to 3.573	0.558
Multisystem inflammatory syndrome in children	1.356	–1.827 to 4.540	0.404
Acute respiratory distress syndrome	–1.899	–5.318 to 1.520	0.276
Corticosteroids	–2.487	–4.688 to –0.285	0.027
IV immunoglobulin	–3.681	–7.095 to –0.267	0.035

ECMO = extracorporeal membrane oxygenation.