Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
This simplified oncoplot shows the distribution of BRAF and MAP2K1 alterations within the sample cohort, shown in context with the site of action of RAF and MEK in the MAPK pathway. The four categories of variants are annotated to show potential therapeutic strategies, based on extrapolation of data from human studies.
