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. 2023 Apr 25;2023:6359818. doi: 10.1155/2023/6359818

Table 8.

Biological activities found for the ethanol extract of M. capitulata (EEMC) and methanol extracts of T. tricuspidata (METT) and A. campanulatus (MEAC) major compounds by PASS online.

Sample Compound Biological properties predicted by PASS online Pa Pi
EEMC Crassifoside A Antidiabetic 0.696 0.006
Antioxidant 0.620 0.004
Free radical scavenger 0.772 0.003
Breviscaside A Antidiabetic 0.597 0.013
Alpha glucosidase inhibitor 0.637 0.001
Antioxidant 0.495 0.007
Crassifogenin C Insulin promoter 0.279 0.007
Antioxidant 0.615 0.168
Free radical scavenger 0.364 0.021
Crassifoside D Antioxidant 0.509 0.006
Lipid peroxidase inhibitor 0.579 0.010
Free radical scavenger 0.626 0.005
Curcapital Insulin inhibitor 0.483 0.055
Antioxidant 0.291 0.025
Free radical scavenger 0.323 0.026
Isocurculigine Antidiabetic 0.618 0.011
Antioxidant 0.539 0.005
Free radical scavenger 0.669 0.004

METT Cyclotricuspidoside A Antidiabetic 0.417 0.039
Alpha glucosidase inhibitor 0.123 0.018
Antioxidant 0.386 0.013
Cyclotricuspidoside C Antidiabetic 0.362 0.055
Alpha glucosidase inhibitor 0.124 0.017
Antioxidant 0.377 0.014
Stigmast-7-en-3β-ol Alpha glucosidase inhibitor 0.069 0.064
Insulin promoter 0.547 0.021
Antioxidant 0.172 0.077
α-Spinasterol Alpha glucosidase inhibitor 0.069 0.064
Insulin promoter 0.527 0.024
Antioxidant 0.208 0.051
3-o-β-D-glucopyranoside Antioxidant 0.373 0.015
Lipid peroxidase inhibitor 0.305 0.062
Free radical scavenger 0.317 0.027
Glyceryl 1 palmitate Alpha glucosidase inhibitor 0.193 0.005
Insulin promoter 0.444 0.044
Antioxidant 0.276 0.028

MEAC Stigmasterol Insulin promoter 0.347 0.095
Lipid peroxidase inhibitor 0.305 0.062
Antioxidant 0.215 0.048
β-sitosterol Insulin promoter 0.361 0.085
Antioxidant 0.178 0.072
Lipid peroxidase inhibitor 0.237 0.101
Campesterol Insulin promoter 0.332 0.107
Antioxidant 0.182 0.068
Lipid peroxidase inhibitor 0.273 0.077
1,3,5-Benzenetriol Antidiabetic 0.618 0.011
Alpha glucosidase inhibitor 0.418 0.002
Free radical scavenger 0.669 0.004
Vitamin E acetate Antidiabetic symptomatic 0.510 0.007
Antioxidant 0.956 0.002
Free radical scavenger 0.780 0.003
Squalene Antioxidant 0.657 0.004
Lipid peroxidase inhibitor 0.601 0.009
Free radical scavenger 0.456 0.013

Pa = probable activity; Pi = probable inactivity.