TABLE 1.
Vaccination groups used to assess the effects of dose of CFP and IL-2 on immune responses in cattle (experiment 2)
| Vaccine groupa | Dose of CFPb | Dose of IL-2 (μg) | Dose of BCG (CFU) |
|---|---|---|---|
| 1 | |||
| 2 | 50 | ||
| 3 | 250 | ||
| 4 | 200 μg | ||
| 5 | 200 μg | 50 | |
| 6 | 200 μg | 250 | |
| 7 | 1 mg | ||
| 8 | 1 mg | 50 | |
| 9 | 1 mg | 250 | |
| 10 | 106 |
a
Animals in groups 1 to 9 were vaccinated three times at 2-week intervals, and animals in group 10 were vaccinated twice with BCG with a 6-week interval.
b
M. bovis CFP. Vaccines were prepared by combining CFP and IL-2 with MPL adjuvant. Each dose contained 200 μg of MPL.