TABLE 3.

Presence of macroscopic tuberculous lung lesions and lung lesion scores and bacterial counts in cattle following challenge with virulent M. bovis (experiment 3)

Group	No. of cattle with lung lesions/total no.	Lung lesion scorea	Lung bacterial countb
Control	11/11	3.82 ± 0.12	2.53 ± 0.14
BCG-vaccinated	5/10*	1.00 ± 0.39*	1.96 ± 0.32
High-dose CFP–IL-2	8/11	2.09 ± 0.48*	2.63 ± 0.20
Low-dose CFP–IL-2	4/4	2.75 ± 0.63	2.62 ± 0.32

^aMean lung lesion scores in vaccinated and control animals ± SE. Lung lesion score: 4, ≥100 small lesions or a consolidated lesion >60 mm in diameter; 3, 25 to 99 small lesions or a consolidated lesion 20 to 60 mm in diameter; 2, 10 to 24 small lesions; 1, 1 to 9 small lesions; 0, no lesions. *, significantly different from the control (MPL adjuvant only) group (P < 0.05). 

^bGeometric mean for bacterial counts (log₁₀ CFU per gram of tissue) ± SE.