Figure 10.

Histopathology of rat hepatic cells. (A) Normal hepatic cells showing preserved cytoplasm and nucleus, (B) disease rat showed area of hemorrhagic [H] and fatty change [F], (C) treatment with 5 mg/kg of oxadiazole derivative showed hepatic restoration with the congested portal vein [CPV], (D) treatment with 10 mg/kg of 1,3,4-oxadiazole derivative showed fat build up in the liver cells, (E) treatment with 15 mg/kg of 1,3,4-oxadiazole derivative showed restoration of normal hepatic architecture and dilation of the portal [DP] vein, (F) treatment with glimepiride showed recovery of hepatic cell with the dilation of portal vein [DPV], and (G) treatment with acarbose showed DPV with normal hepatic cells.