Figure 4.

Effect of 1,3,4-oxadiazole derivative, glimepiride, and acarbose on the blood glucose level. Alloxanized rats were given either vehicle (carboxy methylcellulose; 1 mg/kg), 1,3,4-oxadiazole derivative (5, 10, and 15 mg/kg), glimepiride (4 mg/kg), or acarbose (40 mg/kg) orally once daily from day 1^st to 14^th day of treatment. The blood glucose levels were measured before alloxan (basal) and on zero (72 h after alloxan), 5^th, 10^th, and 14^th day of various treatments. The data represent mean ± SEM (n = 6). ^∗∗∗P < 0.001, ^∗∗P < 0.01, ^∗P < 0.05 represents significantly different values as compared to the disease control, i.e., alloxanized rats. Note: OXD: 1,3,4-oxadiazole derivative.