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. 2023 Mar 13;3(4):391–401. doi: 10.1038/s43587-023-00380-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — CSF concentrations of p-tau217 (A), p-tau231 (C), p-tau181 by MS (E), p-tau205 (G), and Aβ42 (I) and tau phosphorylation occupancies at T217 (B), T231 (D), T181 (F), T205 (H), as well as Aβ42/Aβ40 (J), are plotted as a function of amyloid PET Centiloid. Spearman correlations with 95% confidence intervals are shown. Vertical dashed lines represent the cut-off for amyloid PET positivity. Each symbol represents one individual: green square: amyloid PET negative, CSF positive, CDR > 0; red circle: amyloid PET positive, CSF positive, CDR = 0.5; red square: amyloid PET positive, CSF positive, CDR > 0.5.