TABLE 3.
Protection of mice immunized with different constructs
| Immunogen construct | No. of survivors/total no. after infection on:
|
Pa | ||
|---|---|---|---|---|
| Day 5 | Day 12 | Day 20 | ||
| Control | 72/72 | 0/72 | 0/12 | |
| pPcMSP119HBs plus pGMCSF | 12/12 | 0/12 | 0/12 | |
| pPcMSP119-HBs plus pIFNγ | 12/12 | 1/12 | 0/12 | |
| rMSP119-GST | 12/12 | 3/12 | 1/12 | >0.05 |
| pPcMSP119-HBs plus pIL-2 | 12/12 | 3/12 | 2/12 | 0.019 |
| pSel-MSP119-HBs | 12/12 | 3/12 | 3/12 | 0.002 |
| pPcMSP119 | 12/12 | 5/12 | 5/12 | 0.00002 |
a
Values were calculated by using the χ2 test applying Fisher exact values and comparing the control group values of day 20 versus the test group values on day 20.