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. 2022 Nov 9;18(8):1818–1826. doi: 10.4103/1673-5374.360242

Figure 11.

Figure 11

Effects of exendin-4 and linagliptin on MPP (+)-induced NLRP3 expression in BV2 cells.

Expression of NLRP3 (green, Alexa Fluor 488) in BV2 cells, as detected by immunofluorescence. The intensity of the NLRP3 signal was increased in the MPP (+) group and decreased in the MPP (+) + EX-4 and MPP (+) + LINA groups. Scale bar: 50 µm. CON: Control; DAPI: 4,6-diamidino-2-phenylindole; EX-4: exendin-4; LINA: linagliptin; MPP (+): 1-methyl-4-phenylpyridium; NLRP3: nucleotide-binding oligomerization domain- and leucine-rich-repeat- and pyrin-domain-containing 3.