Table 1.
Clinical characteristics of men and women with and without HUA.
| Characteristics | Non-hyperuricemia | p-value | Hyperuricemia | p-value | ||
|---|---|---|---|---|---|---|
| Men | Women | Men | Women | |||
| N | 5,201 | 6,888 | 2,978 | 888 | ||
| Age, years | 44.30 (13.15) | 40.27 (12.60) | <0.001 | 41.20 (12.05) | 44.21 (14.91) | <0.001 |
| BMI, kg/m2 | 25.09 (3.22) | 22.50 (3.37) | <0.001 | 26.76 (3.60) | 24.81 (4.25) | <0.001 |
| SBP, mm/Hg | 124.98 (15.81) | 115.40 (16.56) | <0.001 | 126.83 (15.66) | 121.51 (19.06) | <0.001 |
| DBP, mm/Hg | 74.45 (11.07) | 67.57 (10.40) | <0.001 | 76.38 (11.67) | 71.02 (11.48) | <0.001 |
| FBG, mmol/L | 4.91 (4.55–5.34) | 4.73 (4.44–5.05) | <0.001 | 4.93 (4.58–5.38) | 4.88 (4.51–5.35) | 0.097 |
| HBA1c, % | 5.50 (5.20–5.70) | 5.40 (5.20–5.60) | <0.001 | 5.50 (5.30–5.70) | 5.50 (5.30–5.90) | 0.003 |
| TG, mmol/L | 1.30 (0.95–1.84) | 0.93 (0.71–1.29) | <0.001 | 1.70 (1.18–2.44) | 1.35 (0.93–1.99) | <0.001 |
| TC, mmol/L | 4.81 (4.27–5.40) | 4.73 (4.22–5.35) | 0.072 | 5.00 (4.46–5.62) | 5.07 (4.42–5.69) | 0.181 |
| HDL-C, mmol/L | 1.20 (1.00–1.40) | 1.50 (1.30–1.74) | <0.001 | 1.10 (1.00–1.30) | 1.30 (1.10–1.50) | <0.001 |
| LDL-C, mmol/L | 3.00 (2.47–3.50) | 2.70 (2.20–3.25) | <0.001 | 3.11 (2.60–3.70) | 3.06 (2.50–3.70) | 0.141 |
| UA, μmol/L | 359.00 (322.00–389.00) | 273.00 (240.00–306.00) | <0.001 | 470.00 (443.25–513.00) | 391.00 (373.00–420.00) | <0.001 |
| FT3, pmol/L | 5.14 (0.47) | 4.67 (0.45) | <0.001 | 5.19 (0.48) | 4.71 (0.46) | <0.001 |
| FT4, pmol/L | 16.54 (1.99) | 15.51 (1.83) | <0.001 | 16.73 (2.02) | 15.76 (1.89) | <0.001 |
| TSH, pmol/L | 1.90 (0.83) | 2.16 (0.93) | <0.001 | 1.97 (0.86) | 2.26 (0.99) | <0.001 |
| TFQI | −0.04 (−0.22–0.14) | −0.15 (−0.31–0.03) | <0.001 | −0.01 (−0.20–0.17) | −0.11 (−0.27–0.08) | <0.001 |
| TT4RI | 28.61 (20.93–38.78) | 30.66 (22.23–41.98) | <0.001 | 30.24 (22.04–40.50) | 32.61 (22.92–45.22) | <0.001 |
| TSHI | 2.78 (2.43–3.11) | 2.77 (2.43–3.10) | 0.095 | 2.84 (2.50–3.17) | 2.84 (2.50–3.19) | 0.728 |
| PTHQI | −0.00 (−0.28–0.27) | −0.06 (−0.34–0.18) | <0.001 | 0.04 (−0.23–0.33) | −0.01 (−0.28–0.24) | <0.001 |
| FT3/FT4 ratio | 0.31 (0.29–0.34) | 0.30 (0.28–0.33) | <0.001 | 0.31 (0.29–0.34) | 0.30 (0.27–0.33) | <0.001 |
| Hypertension, n (%) | 964 (18.53%) | 643 (9.34%) | <0.001 | 630 (21.16%) | 168 (18.92%) | 0.148 |
| Diabetes, n (%) | 340 (6.54%) | 133 (1.93%) | <0.001 | 128 (4.30%) | 28 (3.15%) | 0.128 |
| Dyslipidemia, n (%) | 3,068 (58.99%) | 2,698 (39.17%) | <0.001 | 2,246 (75.42%) | 547 (61.60%) | <0.001 |
| Fatty liver, n (%) | 1,852 (35.61%) | 946 (13.73%) | <0.001 | 1,760 (59.10%) | 388 (43.69%) | <0.001 |
Data are expressed as the mean ± SD or median (Q1–Q3) or number (%). Bold indicates p-value < 0.05.
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; HbA1c, glycated hemoglobin; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; UA, uric acid; HUA, hyperuricemia; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyrotropin; TFQI, thyroid feedback quantile-based index; PTFQI, parametric thyroid feedback quantile-based index; TSHI, TSH index; TT4RI, thyrotropin thyroxine resistance index.