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. 2023 Apr 19;14:1132543. doi: 10.3389/fendo.2023.1132543

Table 2.

Linear regression analysis for the association between thyroid parameters and UA levels in a euthyroid population.

Variables Model 1 Model 2 Model 3
β (95% CI) p-value β (95% CI) p-value β (95% CI) p-value
Men
FT3 0.151 (0.102, 0.200) <0.001 −0.025 (−0.073, 0.024) 0.320 −0.066 (−0.114, −0.019) 0.006
FT4 0.099 (0.061, 0.137) <0.001 0.072 (0.036, 0.108) <0.001 0.057 (0.022, 0.093) 0.002
TSH 0.021 (0.011, 0.032) <0.001 0.012 (0.002, 0.022) 0.016 0.010 (0.001, 0.020) 0.035
TFQI 0.058 (0.040, 0.077) <0.001 0.037 (0.019, 0.054) <0.001 0.033 (0.016, 0.050) <0.001
TT4RI 0.028 (0.018, 0.038) <0.001 0.017 (0.007, 0.027) <0.001 0.014 (0.005, 0.024) 0.003
TSHI 0.078 (0.053, 0.102) <0.001 0.049 (0.025, 0.073) <0.001 0.040 (0.017, 0.063) <0.001
PTHQI 0.037 (0.026, 0.049) <0.001 0.022 (0.011, 0.033) <0.001 0.020 (0.009, 0.030) <0.001
FT3/FT4 ratio −0.008 (−0.043, 0.027) 0.646 −0.072 (−0.105, −0.039) <0.001 −0.079 (−0.112, −0.047) <0.001
Women
FT3 0.068 (0.018, 0.118) 0.008 0.055 (0.006, 0.103) 0.028 0.027 (−0.021, 0.074) 0.266
FT4 0.149 (0.108, 0.190) <0.001 0.203 (0.164, 0.243) <0.001 0.182 (0.143, 0.221) <0.001
TSH 0.019 (0.008, 0.030) <0.001 0.014 (0.004, 0.024) 0.008 0.012 (0.002, 0.023) 0.016
TFQI 0.085 (0.066, 0.105) <0.001 0.101 (0.082, 0.120) <0.001 0.091 (0.073, 0.110) <0.001
TT4RI 0.029 (0.018, 0.039) <0.001 0.027 (0.017, 0.038) <0.001 0.024 (0.014, 0.034) <0.001
TSHI 0.088 (0.063, 0.114) <0.001 0.093 (0.068, 0.118) <0.001 0.083 (0.059, 0.107) <0.001
PTHQI 0.050 (0.038, 0.063) <0.001 0.055 (0.043, 0.068) <0.001 0.050 (0.038, 0.062) <0.001
FT3/FT4 ratio −0.087 (−0.125, −0.050) <0.001 −0.141 (−0.177, −0.104) <0.001 −0.138 (−0.174, −0.102) <0.001

Data are expressed as standardized coefficients (β) and 95% CI. Continuous variables with a non-normal distribution (UA, FT3, FT4, TSH, TFQI, TT4RI, TSHI, PTHQI, and FT3/FT4 ratio) were log transformed for analysis.

Model 1: Crude model.

Model 2: Adjusted for age and BMI.

Model 3: Adjusted for age, BMI, diabetes, dyslipidemia, fatty liver, and hypertension.