Table 5.
Ectocervical p24 antigen production after ex vivo HIV infection at baseline and 4 hours post dosing.
| P24 antigen production variable (pg/mL) | Baseline Visit 2 (n = 16 ectocervical biopsies among 8 participants) | Post Treatment Visit 3 (4 hours post dosing for Group 1) (n = 16 ectocervical biopsies among 8 participants) | P value | ||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Median | Mean | SD | Median | ||
| p24 Area Under Curve | 4697.19 | 10830.75 | 380.9 | 106.5 | 18 | 102 | < 0.01 |
| p24 Cumulative Production | 1687.58 | 3577.12 | 205.72 | 39 | 12 | 36 | < 0.01 |
| p24 Day 21 of tissue culture | 594.7 | 934.84 | 124.14 | 9 | 12 | 6 | < 0.01 |