Figure 1.

Different outcomes of single-sex schistosome-induced hepatic fibrosis. (A) Bisexual schistosome infection leads to severe liver fibrosis with large granuloma size and massive parasite/egg burden; (B) Bisexual schistosome infection after female infection leads to regressed liver fibrosis with smaller granuloma size, but no change in parasite/egg burden; (C) Bisexual schistosome infection after male infection leads to regressed liver fibrosis with regressed parasite/egg burden, but no change in granuloma size. This figure was created with Biorender.com. Arrows indicate the result of the next step.