Table 2.
Comparison of reported severe cute respiratory syndrome coronavirus 2 cases versus serology-based estimated infections and infection-to-case ratios among children in North Carolina
| Month (2021) | Estimated seroprevalence (95% CrI) | Cumulative reported cases prior montha | Average estimated infections | Infection/reported case ratio (95% CrI) |
|---|---|---|---|---|
| May | 15.2 (9.0–22.0) | 99,046 | 308,500 (183,400–446,600) | 3.1 (1.9–4.5) |
| June | 34.4 (27.2–41.9) | 106,251 | 639,700 (505,500–777,500) | 6.0 (4.8–7.3) |
| July | 34.2 (28.1–40.1) | 108,016 | 620,100 (509,100–727,600) | 5.7 (4.7–6.7) |
| August | 40.5 (34.5–46.4) | 116,979 | 708,300 (602,100–810,000) | 6.1 (5.1–6.9) |
| September | 39.2 (32.3–45.9) | 147,831 | 676,200 (556,400–791,800) | 4.6 (3.8–5.4) |
| October | 54.1 (46.7–61.1) | 193,676 | 926,600 (800,800–1,046,700) | 4.8 (4.1–5.4) |
Abbreviation: CrI, credible interval.
a
Cumulative coronavirus disease 2019 cases reported by the North Carolina Department of Health and Human Services based on the prior month (e.g., seroprevalence estimate for May are compared to cases in April to allow time for development of IgG antibodies).