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. 2023 Apr 19;14:1177722. doi: 10.3389/fimmu.2023.1177722

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Copyright © 2023 Solé, Parras, Yamanouchi, Garnica, Garabatos, Moro, Montaño, Mondal, Fandos, Yang, Serra and Santamaria

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Reversal of hyperglycemia by insulin_9-23/IA^g7-NPs in newly diabetic NOD mice. (A, B) Evolution of average (A) and individual (B) blood glucose levels in diabetic female NOD mice treated with vehicle (n=5) or InsB_12-20-CT-R1/IA^g7-, InsB_13-21-R2/IA^g7- or InsB_10-23-CT-R3/IA^g7-NPs (n=5, 3 and 2, respectively). Data were compared via two-way ANOVA.