Table 3.
Associations between gut inflammation markers and markers of inflammasome activation (Spearman correlations)
| Patients | MAdCAM-1 | I-FABP | CCL25 | LBP | ||||
|---|---|---|---|---|---|---|---|---|
| rho | P | rho | P | rho | P | rho | P | |
| IL-18 | ||||||||
| HC | 0.01 | .791 | 0.06 | .250 | 0.01 | .821 | 0.10 | .050 |
| SCZ+AFF | 0.07 | .077 | 0.03 | .539 | 0.05 | .229 | 0.02 | .708 |
| SCZ | 0.03 | .559 | −0.02 | .729 | 0.01 | .853 | 0.03 | .597 |
| AFF | 0.15 | .050 | 0.16 | .039 | 0.14 | .068 | −0.01 | .896 |
| IL-18BPa | ||||||||
| HC | 0.05 | .285 | 0.01 | .859 | 0.01 | .866 | −0.00 | .985 |
| SCZ+AFF | 0.11 | .008 | 0.17 | <.001 | 0.04 | .421 | 0.02 | .556 |
| SCZ | 0.12 | .021 | 0.16 | .002 | 0.07 | .204 | 0.02 | .704 |
| AFF | 0.06 | .434 | 0.24 | .001 | −0.04 | .594 | 0.05 | .498 |
| NLRP3 | ||||||||
| HC | 0.07 | .294 | 0.04 | .553 | −0.06 | .408 | −0.01 | .875 |
| SCZ+AFF | 0.02 | .736 | −0.02 | .734 | 0.00 | .994 | 0.15 | .005 |
| SCZ | 0.01 | .850 | −0.07 | .295 | −0.07 | .305 | 0.15 | .020 |
| AFF | 0.03 | .729 | 0.07 | .439 | 0.12 | .188 | 0.14 | .112 |
| NLRC4 | ||||||||
| HC | 0.03 | .607 | −0.10 | .125 | −0.04 | .577 | 0.12 | .053 |
| SCZ+AFF | 0.06 | .284 | −0.05 | .377 | 0.02 | .662 | 0.19 | <.001 |
| SCZ | 0.03 | .660 | −0.09 | .178 | 0.00 | .993 | 0.22 | <.001 |
| AFF | 0.10 | .247 | 0.02 | .839 | 0.05 | .584 | 0.14 | .132 |
Bold = P < .0031.