TABLE 3.
Univariate and multivariate analyses of prognostic factors in esophageal squamous cell carcinoma (ESCC) patients who received neoadjuvant chemotherapy.
| 5‐year overall survival | ||||||
|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||||
| Variable | Hazard ratio | (95% CI) | p‐Value* | Hazard ratio | (95% CI) | p‐Value* |
| Age (<60 year/>60 year) | 1.621 | (0.715–3.677) | 0.248 | |||
| Sex (Female/Male) | 0.730 | (0.323–1.654) | 0.450 | |||
| Histological type (differentiated/undiferentiated) | 1.414 | (0.753–2.655) | 0.273 | |||
| Location (Ut, Mt/Lt) | 0.835 | (0.423–1.650) | 0.604 | |||
| pT category (T1‐2/T3‐4) a | 1.847 | (0.965–3.536) | 0.064 | |||
| pN category (N1/2–3) a | 2.122 | (1.068–4.214) | 0.0317* | |||
| pStage (II/III + IV) a | 3.565 | (1.258–10.10) | 0.0167* | 2.995 | (1.047–8.568) | 0.0408* |
| Lymphatic invasion (Ly−/Ly+) | 2.322 | (1.064–5.069)) | 0.0344* | |||
| Venous invasion (V−/V+) | 1.531 | (0.773–3.031) | 0.222 | |||
| CD103 (high/low) in primary lesions | 0.612 | (0.319–1.172) | 0.138 | |||
| CD103 (high/low) in metastatic LNs | 0.380 | (0.185–0.783) | 0.009* | 0.442 | (0.213–0.915) | 0.0279* |
*
Cox proportional hazard mode; p < 0.05, statistically significant.
a
TNM classification of esophageal squamous cell carcinoma, 8th ed.