TABLE 1.
The correlation between GNB1 expression and clincopathological features in hepatocellular carcinoma (HCC)
| Clinical variables | Number of patients | GNB1 expression level | p value | |
|---|---|---|---|---|
| n = 91 | Low (n = 59) | High (n = 32) | ||
| Age (years) | 0.476 | |||
| <60 | 72 | 48 (66.7%) | 24 (33.3%) | |
| ≥60 | 19 | 11 (57.9%) | 8 (42.1%) | |
| Gender | 0.307 | |||
| Male | 76 | 51 (67.1%) | 25 (32.9%) | |
| Female | 15 | 8 (53.3%) | 7 (46.7%) | |
| HBsAg | 0.428 | |||
| Positive | 75 | 50 (66.7%) | 25 (33.3%) | |
| Negative | 16 | 9 (56.3%) | 7 (43.7%) | |
| ALT (U/L) | 0.907 | |||
| ≤40 | 59 | 38 (64.4%) | 21 (35.6%) | |
| >40 | 32 | 21 (65.6%) | 11 (34.4%) | |
| AST (U/L) | 0.926 | |||
| ≤40 | 62 | 40 (64.5%) | 22 (35.5%) | |
| >40 | 29 | 19 (65.5%) | 10 (34.5%) | |
| AFP (ng/mL) | 0.735 | |||
| <400 | 49 | 31 (63.3%) | 18 (36.7%) | |
| ≥400 | 42 | 28 (66.7%) | 14 (33.3%) | |
| Child–Pugh class | 0.014 | |||
| A | 81 | 49 (60.5%) | 32 (39.5%) | |
| B | 10 | 10 (100%) | 0 (0%) | |
| Liver cirrhosis | 0.170 | |||
| No | 25 | 19 (76.0%) | 6 (24.0%) | |
| Yes | 66 | 40 (60.6%) | 26 (39.4%) | |
| Tumor size (cm) | 0.396 | |||
| ≤5 | 29 | 17 (58.6%) | 12 (41.4%) | |
| >5 | 62 | 42 (67.7%) | 20 (32.3%) | |
| Tumor number | 0.582 | |||
| Single | 74 | 47 (63.5%) | 27 (36.5%) | |
| Multiple | 17 | 12 (70.6%) | 5 (29.4%) | |
| Tumor encapsulation | 0.890 | |||
| Yes | 56 | 36 (64.3%) | 20 (35.7%) | |
| No | 35 | 23 (65.7%) | 12 (34.3%) | |
| Vascular invasion | 0.712 | |||
| Yes | 18 | 11 (61.1%) | 7 (38.9%) | |
| No | 73 | 48 (65.8%) | 25 (34.2%) | |
| Tumor differentiation | 0.105 | |||
| Well | 53 | 38 (71.7%) | 15 (28.3%) | |
| Poor | 38 | 21 (55.3%) | 17 (44.7%) | |
| TNM stage | 0.579 | |||
| I–II | 65 | 41 (63.1%) | 24 (36.9%) | |
| III–IV | 26 | 18 (69.2%) | 8 (30.8%) | |