TABLE 2.
The correlation between BAG2 expression and clincopathological features in hepatocellular carcinoma (HCC)
| Clinical variables | Number of patients | BAG2 expression level | p value | |
|---|---|---|---|---|
| n = 91 | Low (n = 40) | High (n = 51) | ||
| Age (years) | 0.736 | |||
| <60 | 72 | 31 (43.1%) | 41 (56.9%) | |
| ≥60 | 19 | 9 (47.4%) | 10 (52.6%) | |
| Gender | 0.364 | |||
| Male | 76 | 35 (46.1%) | 41 (53.9%) | |
| Female | 15 | 5 (33.3%) | 10 (66.4%) | |
| HBsAg | 0.985 | |||
| Positive | 75 | 33 (44%) | 42 (56%) | |
| Negative | 16 | 7 (43.8%) | 9 (56.2%) | |
| ALT (U/L) | 0.632 | |||
| ≤40 | 59 | 27 (45.8%) | 32 (54.2%) | |
| >40 | 32 | 13 (40.6%) | 19 (59.4%) | |
| AST (U/L) | 0.009 | |||
| ≤40 | 62 | 33 (53.2%) | 29 (46.8%) | |
| >40 | 29 | 7 (24.1%) | 22 (75.9%) | |
| AFP (ng/mL) | 0.021 | |||
| <400 | 49 | 27 (55.1%) | 22 (44.9%) | |
| ≥400 | 42 | 13 (31.0%) | 29 (69.0%) | |
| Child–Pugh class | 0.789 | |||
| A | 81 | 36 (44.4%) | 45 (55.6%) | |
| B | 10 | 4 (40.0%) | 6 (60.0%) | |
| Liver cirrhosis | 0.347 | |||
| No | 25 | 9 (36.0%) | 16 (64.0%) | |
| Yes | 66 | 31 (47.0%) | 35 (53.0%) | |
| Tumor size (cm) | 0.307 | |||
| ≤5 | 29 | 15 (51.7%) | 14 (48.3%) | |
| >5 | 62 | 25 (40.3%) | 37 (59.7%) | |
| Tumor number | 0.060 | |||
| Single | 74 | 36 (48.6%) | 38 (51.4%) | |
| Multiple | 17 | 4 (23.5%) | 13 (76.5%) | |
| Tumor encapsulation | 0.015 | |||
| Yes | 56 | 19 (33.9%) | 37 (66.1%) | |
| No | 35 | 21 (60.0%) | 14 (40.0%) | |
| Vascular invasion | 0.311 | |||
| Yes | 18 | 6 (33.3%) | 12 (66.7%) | |
| No | 73 | 34 (46.6%) | 39 (53.4%) | |
| Tumor differentiation | 0.247 | |||
| Well | 53 | 26 (49.1%) | 27 (50.9%) | |
| Poor | 38 | 14 (36.8%) | 24 (63.2%) | |
| TNM stage | 0.003 | |||
| I–II | 65 | 35 (53.8%) | 30 (46.2%) | |
| III–IV | 26 | 5 (19.2%) | 21 (80.8%) | |