TABLE 1.
Patient and first AP attack characteristics
| Patient characteristics | All N = 112 |
|---|---|
|
| |
| Institution | |
| NCH | 69 (62%) |
| CCHMC | 43 (38%) |
| Age, y, for first attack | 11.5 (5.0–16.0) [min–max: 0–36] |
| Sex (male) | 56 (50%) |
| Underlying diagnosis | |
| Cerebral palsy/spastic quadriplegia | 73 (65%) |
| Diabetes | 4 (3.6%) |
| Seizures | 75 (67%) |
| Mitochondrial disease | 3 (3%) |
| Chromosomal abnormalities | 26 (23%) |
| Other | 65 (58%) |
| Multiple underlying diagnoses | 99 (88%) |
| Family history of pancreatitis | |
| Yes | 2 (2%) |
| No | 84 (75%) |
| Unknown | 26 (23%) |
| First AP attack characteristics | |
| Classification of pancreatitis (first attack) | |
| Acute pancreatitis | 110 (98%) |
| Chronic pancreatitis | 2 (2%) |
| Age, y, by diagnosis | |
| Acute pancreatitis | 12.0 (5.0–16.0) |
| Chronic pancreatitis | 7.5 (7.0–8.0) |
| Signs and symptoms | |
| Abdominal pain | 56 (50%) |
| Vomiting | 38 (34%) |
| Diarrhea | 21 (19%) |
| Feeding intolerance | 25 (22%) |
| Other | 69 (62%) |
| Multiple signs and symptoms | 82 (73%) |
| Imaging | |
| CT | 41 (37%) |
| Ultrasound | 58 (52%) |
| MRI | 5 (4%) |
| None | 18 (16%) |
| Any imaging | 94 (84%) |
| Multiple imaging | 10/94 (11%) |
| Imaging show pancreatitis | |
| Yes | 22/94 (23%) |
| No | 72/94 (77%) |
| Severity of attack | |
| Mild | 92 (82%) |
| Moderate | 6 (5%) |
| Severe | 14 (13%) |
Data presented as n (%) or median (25th–75th percentile) [min–max]. AP = acute pancreatitis; CCHMC = Cincinnati Children’s Hospital Medical Center; CT = computed tomography; MRI = magnetic resonance imaging; NCH = Nationwide Children’s Hospital.