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. Author manuscript; available in PMC: 2024 Feb 22.
Published in final edited form as: Subst Use Misuse. 2023 Feb 22;58(5):591–600. doi: 10.1080/10826084.2023.2177110

Table 4.

Associations between symptoms of anxiety and depression and past 30-day e-cigarette use, stratified by grade level

E-cigarette use with nicotine at 12-month follow-up E-cigarette use with THC at 12-month follow-up
10th grade 12th grade 2 years post high school 10th grade 12th grade 2 years post high school
AORa (95% CI) AORa (95% CI) AORa (95% CI) AORb (95% CI) AORb (95% CI) AORb (95% CI)
Total n n=652 n=781 n=874 n=652 n=781 n=874
Comorbidityd 2.10 (0.86, 5.13) 1.73 (0.89, 3.36) 1.25 (0.67, 2.33) 0.87 (0.34, 2.19) 1.76 (0.87, 3.58) 1.69 (0.98, 2.90)
Depressione 1.56 (0.69, 3.53) 1.53 (0.85, 2.75) 1.11 (0.65, 1.90) 0.93 (0.42, 2.03) 2.04* (1.13, 3.69) 1.66* (1.03, 2.66)
Anxietyf 2.24 (0.99, 5.03) 1.86* (1.02, 3.38) 1.26 (0.71, 2.24) 0.73 (0.32, 1.69) 1.48 (0.77, 2.84) 1.30 (0.77, 2.19)
a

Adjusted for sex, race/ethnicity, SES, and Wave 9 (baseline) past 30-day use of e-cigarettes with nicotine, marijuana in any form, alcohol, and combustible tobacco.

b

Adjusted for sex, race/ethnicity, SES, and Wave 9 (baseline) past 30-day use of e-cigarettes with THC, marijuana in any other form, alcohol, and combustible tobacco.

c

Adjusted for grade level, race/ethnicity, SES, and Wave 9 (baseline) past 30-day use of e-cigarette with nicotine, e-cigarettes with THC, marijuana in any other form, alcohol, and combustible tobacco.

d

Comorbidity is symptoms of depression and anxiety present at Wave 9 (baseline).

e

Symptoms of depression measured at Wave 9 (baseline) using the PHQ-9, with scores ≥10 indicating a positive screen for depression symptoms.

f

Symptoms of anxiety measured at Wave 9 (baseline) using the GAD-7, with scores ≥10 indicating a positive screen for anxiety symptoms.

Boldface indicates statistical significance (*p<0.05, **p<0.01, ***p<0.001).

Referent group is no symptoms of anxiety or depression.

AOR, adjusted odds ratio; CI, confidence interval.