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. 2023 May 3;16:46. doi: 10.1186/s13045-023-01442-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — Tumor hybrid cells are sensitive to radiotherapy. a Clonogenic survival curves were constructed according to the survival fractions of RM1 and hybrid cells after receiving different doses of irradiation. b Survival rate of RM1 cells and tumor hybrid cells at different time points after receiving 6 Gy irradiation, normalized to the untreated group. c. Schematic illustration of the experimental design used for radiotherapy. d The growth curve of RM1 tumor or hybrid tumors after treatment with 8 Gy irradiation (n = 6). e Tumor weight measured at the endpoint of the experiment after treatment with radiotherapy (n = 6). f The growth curve of body weights in mice receiving radiotherapy and not (n = 6). ***P < 0.001