. Author manuscript; available in PMC: 2024 Feb 1.

Published in final edited form as: Nat Neurosci. 2023 Jan 2;26(2):181–195. doi: 10.1038/s41593-022-01222-2

Table 1.

Single-cell transcriptomic and epigenetic datasets from post-mortem AD tissue.

Study	Data ID	Patient cohort	Brain region	Sequencing strategy	Total nuclei
^♦Mathys⁸	syn18485175	48	PFC (BA10)	snRNA-seq	80,660
Davila¹³	N/A	112	Hippocampus	snRNA-seq	489,558
Davila¹³	N/A	112	Entorhinal cortex	snRNA-seq	489,558
^♦Grubman⁷	GSE138852	12	Entorhinal cortex	snRNA-seq	13,214
^♦Leng¹⁸	GSE147528	10	Caudal entorhinal cortex	snRNA-seq	42,528
^♦Leng¹⁸	GSE147528	10	Superior frontal gyrus	snRNA-seq	63,608
Zhou⁹	syn21125841	32	Dorsolateral prefrontal cortex	snRNA-seq	66,311
Lau¹⁴	GSE157827	21	PFC (BA6, BA8, and BA9)	snRNA-seq	169,496
Otero-Garcia¹²	GSE129308	8	Prefrontal cortex (BA9)	AT8 and MAP2 FACS	63,110
Alsema¹²⁷	GSE146639	27	superior parietal lobe superior frontal gyrus	CD11/CD45 FACS; bc-Smart-seq2
Marinaro¹²⁸	N/A	12	PFC (BA9)	FACS neurons and glia; snRNA-seq	89,325
^♦Yang¹¹⁶	GSE163577	17	hippocampus	Vascular enriched fraction then snRNA-seq	143,793
^♦Yang¹¹⁶	GSE163577	8	superior frontal cortex	Vascular enriched fraction then snRNA-seq	143,793
Gerrits¹²⁹	GSE148822	18	occipitotemporal cortex and fusiform gyrus	NEUN⁻/OLIG2⁻ FACS, then snRNA-seq	482,472 nuclei
Del-Aguila¹³⁰	http://ngi.pub/snuclRNA-seq/	3	Parietal lobe	snRNA-seq	26,331
Olah¹³¹		14	dorsolateral prefrontal cortex	CD11b+/CD45+, snRNA-seq	16,242
Olah¹³¹		3	TNC	CD11b+/CD45+, snRNA-seq	16,242
^♦Morabito⁷⁷	syn3219045	20	PFC	snATAC-seq and snRNA-seq	191,890
Xu¹³²	GSE181279	5	PBMCs	CD45 selection, then TCR-seq	36,849
Gate¹³³	GSE134578	18	peripheral CD8+ TEMRA; CSF cells	TCR-seq	21,267
Smith¹³⁴	GSE160936	12	entorhinal and somatosensory cortex	NEUN-/SOX10-	52,706 astrocytes and 27,592 microglia

^♦

signifies particularly noteworthy study