Table 3.
Correlation Between Modified Rankin Scale and Other Variables Using Spearman Correlation Coefficient and Linear Regression Analysis in Aneurysmal Subarachnoid Hemorrhage
| Variable | r | P value | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|---|---|
| t | Beta | P value | t | Beta | P value | |||
| Gender (male/female) | 0.020 | 0.823 | 0.187 | 0.017 | 0.852 | – | ||
| Age (years) | 0.090 | 0.321 | 0.607 | 0.055 | 0.545 | – | ||
| Cigarette smoking | 0.035 | 0.703 | 0.300 | 0.027 | 0.765 | – | ||
| Alcohol consumption | −0.053 | 0.562 | −0.512 | −0.046 | 0.610 | – | ||
| Hypertension | 0.081 | 0.374 | 0.847 | 0.077 | 0.399 | – | ||
| Diabetes mellitus | 0.014 | 0.876 | 0.221 | 0.020 | 0.825 | – | ||
| Hyperlipidemia | 0.065 | 0.473 | 0.788 | 0.071 | 0.432 | – | ||
| WFNS score | 0.660 | <0.001* | 9.930 | 0.670 | <0.001* | 2.943 | 0.293 | 0.004* |
| Modified Fisher score | 0.614 | <0.001* | 9.208 | 0.642 | <0.001* | 2.076 | 0.200 | 0.040* |
| Aneurysmal position (posterior / anterior circulation) | −0.157 | 0.084 | −1.680 | −0.151 | 0.095 | – | ||
| Aneurysmal shape (cystic/others) | −0.013 | 0.889 | −0.515 | −0.047 | 0.608 | – | ||
| Aneurysmal diameter (<10 mm/≥10 mm) | 0.053 | 0.562 | 0.761 | 0.069 | 0.448 | – | ||
| Surgery (clipping/ endovascular intervention) | 0.035 | 0.704 | 0.551 | 0.050 | 0.582 | – | ||
| Intraventricular bleeding | 0.394 | <0.001* | 5.057 | 0.418 | <0.001* | 1.430 | 0.104 | 0.155 |
| Acute hydrocephalus | 0.267 | 0.003* | 3.408 | 0.296 | 0.001* | 1.678 | 0.112 | 0.096 |
| External ventricular drain | 0.129 | 0.155 | 1.774 | 0.159 | 0.079 | – | ||
| Admission time (h) | −0.113 | 0.215 | −1.304 | −0.118 | 0.195 | – | ||
| Blood-collection time (h) | −0.124 | 0.173 | −1.447 | −0.130 | 0.150 | - | ||
| Systolic arterial pressure (mmHg) | −0.084 | 0.357 | −0.862 | −0.078 | 0.390 | - | ||
| Diastolic arterial pressure (mmHg) | 0.045 | 0.623 | 0.199 | 0.018 | 0.842 | - | ||
| Blood leucocyte count (×109/L) | 0.324 | <0.001* | 3.502 | 0.303 | 0.001* | 0.808 | 0.053 | 0.421 |
| Blood potassium concentrations (mmol/L) | −0.079 | 0.385 | −0.799 | −0.072 | 0.426 | - | ||
| Blood glucose concentrations (mmol/L) | 0.222 | 0.014* | 3.154 | 0.276 | 0.002* | 1.253 | 0.081 | 0.213 |
| Serum NOX2 levels (pg/mL) | 0.563 | <0.001* | 8.071 | 0.592 | <0.001* | 2.567 | 0.211 | 0.012* |
Notes: Correlations were done using Spearman correlation coefficient and Linear regression model in aneurysmal subarachnoid hemorrhage. The asterisk indicates statistical significance (*P<0.05).
Abbreviations: WFNS, World Federation of Neurological Societies Scale; NOX2, NADPH oxidase 2.