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Increased nuclear accumulation of YAP/TAZ in the absence of PC1. (A) Representative western blotting images of YAP, phospho-YAP, TAZ and phospho-TAZ in ciliated Pkd1+/- and Pkd1-/- cells. (B) Relative intensities of phospho-Yap to Yap and phospho-TAZ to TAZ. Error bars indicates standard deviation of three independent experiments (*P < 0.05, **P < 0.01; Student’s t test). (C) Immunofluorescence staining of YAP/TAZ (green), acetylated α-tubulin (red), and DAPI (blue). Scale bar: 25μm.
