Table 1.
Demographic and clinical characteristics of amyloid positive and negative individuals
| Amyloid negative (A-) | Amyloid positive (A+) | |
|---|---|---|
| n = 469 | n = 232 | |
| Males, N (%) | 183 (39) | 109 (47.0) |
| Age, Mean (SD) | 64.34 (6.93) | 65.23 (7.17) |
| CDR = 0.5, N (%) | 59 (12.7) | 50 (21.6) |
| MMSE, Mean (SD) | 28.85 (1.44) | 28.65 (1.69) |
| Hippocampal Volume in mm3, Mean (SD) | 2926.59 (472.40) | 2817.46 (490.26) |
| Years of Education, mean (SD) | 14.69 (3.79) | 14.57 (3.86) |
| RBANS | ||
| Total Scale, Mean (SD) | 104.98 (12.54) | 102.27 (13.65) |
| Sum of Index, Mean (SD) | 518.50 (43.16) | 508.51 (48.99) |
| Attention, Mean (SD) | 100.03 (15.28) | 97.66 (15.71) |
| Delayed Memory, Mean (SD) | 103.70 (12.53) | 101.49 (15.09) |
| Language, Mean (SD) | 99.66 (9.62) | 98.12 (11.00) |
| Visuo-Construction, Mean (SD) | 109.22 (15.26) | 107.44 (15.07) |
| Immediate Memory, Mean (SD) | 105.95 (12.99) | 103.80 (14.71) |
Maximum CDR in the EPAD cohort is 0.5, therefore the number (and percentage) of CDR = 0.5 is reported. Abbreviations: SD = Standard Deviation; MMSE = Mini-mental state examination; CDR = clinical dementia rating scale; RBANS = The Repeatable Battery for the Assessment of Neuropsychological Status.