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. 2023 Apr 11;12:e79862. doi: 10.7554/eLife.79862

Table 2. Values of the parameters used in the vertex model with active junctions.

Units: length (a), time (t*=ζ/(Γ+k)), force (f*=(Γ+k)a).

Base
Parameter Description
a Hexagonal cell edge length
Γ Perimeter modulus
k Spring constant
ζ Friction with substrate
Model
Parameter Description Value range
κ Area modulus 1f*/a3
A0 Target cell area 33a2/2
P0 Target cell perimeter 6a
fpull Pulling force 0.0-0.3f*
β Myosin activity 0.0-1.4f*
τv Viscoelastic time 100-103t*
τm Myosin time 101-103t*
T* Threshold tension 0.3f*
K0 Slope of m vs. T at T 2/T*
m0 Myosin reference level 0.5
M Total cell myosin 6
f Variance of myosin fluctuations 1
α Tension-independent myosin dissociation 0.1