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. 2023 May 3;14:2553. doi: 10.1038/s41467-023-37925-8

Table 1.

Origin and relevant physicochemical properties of the polysaccharides used in this work

Bacterial origin Name Mw a (kDa) Intrinsic viscositya [η] (dl/g) Charge index ib
Escherichia coli CFT073 G2cps 780 5 0.5
Salmonella Typhi Vi 280 10 1
Haemophilus influenzae serotype b PRP 550 10 0.5
Neisseria meningitidis serogroup A MenA 200 10 1
Neisseria meningitidis serogroup C MenC 200 10 1
Neisseria meningitidis serogroup Y MenY 600 10 0.5
Neisseria meningitidis serogroup W135 MenW135 500 12 0.5
Streptococcus pneumoniae serotype 12 F PnPS12F 1000 10 0.16
Streptococcus pneumoniae serotype 18 C PnPS18C 300 3 0.2
Streptococcus pneumoniae serotype 1 PnPS1 500 4 0.33
Streptococcus pneumoniae serotype 3 PnPS3 700 7 0.5
Streptococcus pneumoniae serotype 9 V PnPS9V 500 2 0.2
Streptococcus pneumoniae serotype 8 PnPS8 300 6 0.25
Streptococcus pneumoniae serotype 19 A PnPS19A 250 1 0.33
Streptococcus pneumoniae serotype 7 F PnPS7F 1000 1 0
Streptococcus pneumoniae serotype 22 F PnPS22F 800 2 0.2
Streptococcus pneumoniae serotype 14 PnPS14 500 1 0
Streptococcus pneumoniae serotype 2 PnPS2 1300 5 0.17
Streptococcus pneumoniae serotype 4 PnPS4 400 4 0.25
Streptococcus pneumoniae serotype 5 PnPS5 200 3 0.2
Streptococcus pneumoniae serotype 6B PnPS6B 1150 3 0.25
Streptococcus pneumoniae serotype 9 N PnPS9N 700 2 0.2
Streptococcus pneumoniae serotype 10A PnPS10A 550 2 0.14
Streptococcus pneumoniae serotype 11 A PnPS11A 1000 3 0.25
Streptococcus pneumoniae serotype 15B PnPS15B 800 2 0.2
Streptococcus pneumoniae serotype 17 F PnPS17F 900 3 0.14
Streptococcus pneumoniae serotype 19 F PnPS19F 650 3 0.33
Streptococcus pneumoniae serotype 20 PnPS20 600 2 0.17
Streptococcus pneumoniae serotype 23 F PnPS23F 1200 5 0.25
Streptococcus pneumoniae serotype 33 F PnPS33F 1000 2 0
noncapsulated Streptococcus pneumoniae strain CSR SCS2 CWPS Nd Nd Nd

Indicated numbers correspond to mean values.

aThe relative standard deviation of Mw and [η] determination is <10%.

In bold: active broad spectrum antibiofilm polysaccharides. Underlined: active narrow spectrum antibiofilm polysaccharides.

bThe charge index i corresponds to the ratio of the number of acidic group to the number of monosaccharide residue in a repeating unit.

Nd, Not determined.