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. 2023 Mar 27;33(5):389–402. doi: 10.1038/s41422-023-00795-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Summary of confirmed responses according to RECIST v1.1 in each arm in the ITT population. b Forest plots of the ORR and 95% CI of each arm in the ITT population. c Durability of response among 42 patients with a confirmed objective response. The dashed line is at 24 weeks of treatment. d Forest plots of the DCR and 95% CI of each arm in the ITT population. e, f Kaplan‒Meier analysis of PFS (e) and OS (f) in the ITT population. RECIST response evaluation criteria in solid tumors, NE not evaluated, CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR objective response rate, ITT intention-to-treat, CI confidence interval, DCR disease control rate.