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. 2023 Apr 20;11:1147676. doi: 10.3389/fcell.2023.1147676
KRAS-WT the wild type of KRAS
KRAS-MUT the mutation of KRAS
GAP GTPase activating protein
GDP Guanine ribonucleoside diphosphate
GTP Guanine ribonucleoside triphosphate
GEF Guanine nucleotide exchange factor
PI3K Phosphatidylinositol 3-kinase
AKT protein kinase B
mTOR Mechanistic target of rapamycin
RAF Serine/threonine protein kinase
MEK Mitogen-activated protein kinase kinase
ERK extracellular signal-regulated kinase
RALA/RALB v-ral simian leukemia viral oncogene homolog A/B
PLC phospholipase C
PDK1 pyruvate dehydrogenase kinase
MYC myelocytomatosis oncogene
CDK5 Cyclin—dependent Kinase 5
YAP Yes-Associated Protein
JAK Janus Kinase
STAT3 Signal transducer and activator of transcription 3
AURKA The mitotic kinase aurora A
TPX2 Targeting protein for xenopus kinesin-like protein 2
GATA6 Zinc finger transcription factor 6
EGFR epi-dermal growth factor
ALK4 Anaplastic lymphoma kinase 4
ATDC ataxia capillaries group D complementary gene
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
LIF Leukemia inhibitory factor
GLUT1 Glucose transporter 1
Nix Alias
BNIP3a adenovirus E1B 19 kDa interacting protein 3-like
FBW7 F-box and WD repeat domain-containing 7
JAK1 Ja-nus Kinase 1
STAT6 Signal transducer and activator of transcription 6
cMyc c-myelocytomatosis oncogene
NOX4 NADPH oxidase 4
GLUL glutamate-ammonia ligase
NRF2 Nuclear factor erythroid 2-related factor
PIN1 Protein NIMA-interacting 1
MDH1 malate dehydrogenase 1
FGL1 Fibrinogen-like 1
FGF21 Fibroblast growth factor 21
HSL Hormone-sensitive lipase
CXCR2 Chemokine (C-X-C motif) receptor 2
AP1 Jun proto-oncogene
IL10 Interleukin 10
TGFβ Transforming growth factor β
LIPH lipase H
PD-L1 Programmed cell death 1 ligand 1