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Synergy and ex vivo data. a) In vitro synergy of TDI-8414 and DHA against P. falciparum 3D7. Date was average of two independent experiments and each in duplicates. FIC = fractional inhibitory concentration. b-d) Ex vivo data of compounds 9 (b), 23 (c) and 25 (d) against Plasmodium clinical isolates from patients in Tororo, Uganda. Each circle was an IC50 obtained from a clinical isolate. Data were shown with geometric means with 95% confidence intervals.
