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. 2023 Apr 20;14:1123231. doi: 10.3389/fimmu.2023.1123231

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Copyright © 2023 Wang, Chen, Shi, Luo, Zhang, Yuan, Zhang, Shu, Yu and Tian

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Co-expression analysis of cuproptosis-related genes (CRGs) and immune checkpoint genes (ICGs). (A) Expression levels of ICGs between normal liver tissue and hepatocellular carcinoma (HCC). (B) Differences in the expression of ICGs between low-risk and high-risk groups. (C) Co-expression analysis of CRGs and ICGs. ATP7A, ATP13A2, and SNCA were significantly positively correlated with the expression of ICGs, and a negative correlation between ICGs and COX17 or F5 was observed. ns, no significance.