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. 2023 May 3;158(7):e231112. doi: 10.1001/jamasurg.2023.1112

Table 3. Multivariable Generalized Linear Mixed Models (Binary Logit) of Diagnostic Accuracy With Random Effects for Case.

Diagnostic accuracy methods Faculty vs resident P value BMIa of patient P value Age, y P value Female vs male patient P value
Overall accuracy, OR (95% CI) b
Primary and secondary diagnoses 1.19 (0.86-1.65) .29 1.02 (0.96-1.08) .54 0.97 (0.96-0.99)c <.001 0.62 (0.31-1.25) .18
Primary diagnoses only 1.83 (1.26-2.67)c .002 1.05 (0.98-1.14) .19 0.99 (0.97-1.01) .34 0.78 (0.34-1.79) .56
Secondary diagnoses only 0.57 (0.35-0.93)c .02 0.98 (0.90-1.06) .56 0.93 (0.91-0.96)c <.001 0.61 (0.23-1.65) .33
False-positive rate, OR (95% CI)
Primary and secondary diagnoses 1.37 (0.96-1.97) .08 1.03 (0.99-1.08) .16 1.02 (1.01-1.03)c .001 1.73 (1.00-2.99) .05
Primary diagnoses only 0.94 (0.59-1.51) .81 1.03 (0.96-1.10) .42 1.01 (0.99-1.02) .53 1.28 (0.60-2.76) .52
Secondary diagnoses only 2.11 (1.26-3.54)c .005 1.04 (0.98-1.11) .20 1.04 (1.02-1.06)c <.001 2.29 (1.04-5.03) .04
False-negative rate, OR (95% CI)
Primary and secondary diagnoses 0.31 (0.19-0.51)c <.001 0.88 (0.76-1.00) .06 1.05 (1.02-1.09)c .002 1.04 (0.26-4.20) .95
Primary diagnoses only 0.23 (0.13-0.41)c <.001 0.88 (0.76-1.01) .08 1.02 (0.99-1.06) .23 1.76 (0.37-8.52) .48
Secondary diagnoses only 0.76 (0.27-2.13) .60 0.77 (0.51-1.17) .23 1.28 (1.09-1.50)c .002 0.12 (0.00-10.88) .36

Abbreviation: OR, odds ratio.

a

Calculated as weight in kilograms divided by height in meters squared.

b

For overall accuracy, ORs more than 1 indicate higher accuracy and ORs less than 1 indicate lower accuracy. For false positive rate and false negative rate, ORs more than 1 indicate greater odds of false positives (or false negatives) and ORs less than 1 indicate lower odds of false positives (or false negatives).

c

These data are statistically significant after adjustment for multiple comparisons (false discovery rate–adjusted P values14,15).