Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 21;55(2):194–201. doi: 10.3724/abbs.2023015

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021.

0

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

PD-L1 is increased in (NHD13)Setd2 ^fl/fl transgenic and (NHD13)Lep-creSetd2 ^fl/fl transgenic mice

(A) Complete blood count (CBC) analysis of WT, (NHD13)Setd2 fl/fl and (NHD13)Lep-creSetd2 fl/fl mice. CBCs were obtained 3 months after transplantation. RBC, hemoglobin. (B) Representative flow cytometry profiles and quantification of the frequencies of the peripheral blood (PB) cells of the WT, (NHD13)Setd2 fl/fl and (NHD13)Lep-creSetd2 fl/fl mice at the indicated erythroid differentiation stages (RI, proerythroblasts; RII, basophilic erythroblasts; RII, chromatophilic erythroblasts; RIV, orthochromatophilic erythroblasts). Representative flow cytometry profiles and quantification of the frequencies of c-kit+ cells in the PB of the indicated mice at 3 months after transplantation. Representative flow cytometry profiles and quantification of the frequencies of PD-L1+ cells in the PB of the indicated mice at 3 months after transplantation. (C) Wright’s staining of BM and spleen cells isolated from mice transplanted for 3 months (100×magnification). Hematoxylin and eosin staining of the BM and spleen of the mice transplanted for 3 months (40×magnification). (D) Immunohistochemistry of spleen of the (NHD13)Lep-creSetd2 fl/fl mice transplanted for 3 months (40×magnification) in CD41 and CD61. Data are expressed as the mean±SD from three experiments. * P<0.05.